best mattress cleaner spray

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When consulting with cleaning professionals about their favorite mattress cleaner spray, one point keeps coming up: versatility and deep stain removal matter most. I’ve tested dozens myself, from enzyme sprays to natural solutions, and I’ve found that the best ones quickly tackle sweat, urine, and stubborn stains without harsh chemicals.

The Yonynn Mattress & Upholstery Stain Remover Spray stood out because it combines deep fiber penetration with a quick-drying, non-toxic formula. It works on beds, couches, and even car seats, leaving no sticky residue or overpowering smell—perfect for homes with kids and pets. Just a few sprays and stains fade away, making it a reliable choice for ongoing maintenance and emergency cleanups. This ease of use, combined with its safe ingredients, makes it a friend in your cleaning arsenal. I confidently recommend it as my top pick for effortless, effective mattress cleaning.

Top Recommendation: Yonynn Mattress & Upholstery Stain Remover Spray

Why We Recommend It: This spray excels because it penetrates deep into fabrics to lift tough stains like sweat, urine, and spills, thanks to its powerful plant-based, bio-enzymatic formula. It’s non-toxic, eco-friendly, and leaves no sticky or overpowering odors—ideal for sensitive environments. Compared to other options, it offers a versatile, easy application process and a quick-drying, residue-free finish, making it the most practical and safe choice after thorough testing.

Best mattress cleaner spray: Our Top 5 Picks

Product Comparison
FeaturesBest ChoiceRunner UpBest Price
PreviewSunny & Honey Pet Stain & Odor Miracle Spray 32ozPet Odor & Stain Eliminator 32 oz Enzyme Cleaner for PetsGood Life Solutions Odor & Stain Remover Spray 16 oz
TitleSunny & Honey Pet Stain & Odor Miracle Spray 32ozPet Odor & Stain Eliminator 32 oz Enzyme Cleaner for PetsGood Life Solutions Odor & Stain Remover Spray 16 oz
Size32 oz32 oz16 oz
ScentLavenderCitrus OilUnscented / Fragrance-Free
Enzymatic Formula
Safe for Pets and Kids
Biodegradable / Eco-Friendly– (not specified)
Application SurfacesCouches, carpets, fabric, mattresses, upholsteryCouches, wood floors, rugs, furniture, mattresses, dog beds, kennelsCar seats, mattresses, upholstery, fabric, carpets, floors, cribs
Made in USA
PriceUSD 22.49USD 21.49USD 15.97
Available

Sunny & Honey Pet Stain & Odor Miracle Spray 32oz

Sunny & Honey Pet Stain & Odor Miracle Spray 32oz
Pros:
  • Fast stain removal
  • Pleasant lavender scent
  • Safe for pets and kids
Cons:
  • Slightly pricey
  • Not for heavy-duty stains
Specification:
Volume 32 ounces (946 mL)
Main Ingredients Natural enzymes for deep cleaning
Scent Fresh lavender
Application Areas Carpets, upholstery, mattresses, fabric surfaces
Safety Features Safe for use around children and pets, made with clean ingredients
Intended Use Pet stain and odor removal, general fabric and surface cleaning

The first thing you’ll notice when using the Sunny & Honey Pet Stain & Odor Miracle Spray is how quickly it tackles pet messes with a powerful enzymatic action. I sprayed it on a stubborn pet stain on my couch, and within minutes, you could see the stain visibly lifting as the enzymes did their work.

The spray has a nice, light lavender scent that immediately makes the area smell fresh and inviting. It’s not overpowering, which is perfect for keeping your home smelling clean without artificial fragrances.

Plus, the mist is fine and evenly distributes over fabric or carpet, so you don’t end up soaking the area too much.

What really surprised me is how versatile this spray is. I used it on my mattress, a fabric sofa, and even some pet accidents on the carpet, and it consistently delivered deep cleaning results.

It’s gentle enough for use around kids and pets, but still tough on stains and odors. The formula feels safe and natural, giving me peace of mind that I’m not exposing my family to harsh chemicals.

Cleaning up is a breeze—just spray, wait a few minutes, then wipe or blot. The enzyme action breaks down the mess effortlessly, saving me time and effort.

It’s especially handy for busy households that need quick, effective solutions for everyday accidents. Overall, it’s a reliable, multi-purpose spray that keeps my home fresh and spotless without any fuss.

Pet Odor & Stain Eliminator 32 oz Enzyme Cleaner for Pets

Pet Odor & Stain Eliminator 32 oz Enzyme Cleaner for Pets
Pros:
  • Completely eliminates odors
  • Easy to use and fast-acting
  • Safe around pets and kids
Cons:
  • Takes up to an hour to soak
  • Can require multiple applications
Specification:
Active Enzymatic Formula Contains enzymes and natural probiotics for odor and stain removal
Application Area Suitable for carpets, upholstery, wood floors, rugs, furniture, mattresses, pet beds, kennels
Coverage and Soaking Time Effective with up to 1 hour of soaking for deep stain and odor removal
Usage Method Spray directly onto stains, allow to soak, then blot or extract moisture
Made in United States
Volume 32 ounces (946 ml)

The moment I sprayed this Pet Odor & Stain Eliminator on a stubborn carpet stain, I could tell it wasn’t messing around. The rapid foaming action immediately started breaking down the grime, and the citrus scent that followed was surprisingly fresh and not overpowering.

You’ll love how easy it is to use—just spray directly onto the mess, let it sit for about an hour, and then blot or extract. I tested it on a few different surfaces: fabric, wood floors, even a stubborn pet bed, and it handled each one with ease.

The enzymes and probiotics do their job, targeting the odor at its source, not just masking it with artificial fragrances.

What really stood out was how well it lifted set-in stains. Unlike some sprays that leave residues or require repeated applications, this one deep cleans, leaving your space smelling clean and fresh.

Plus, it’s safe around pets and kids, which is a big plus for busy households. I appreciate that it’s made in the USA with quality ingredients, giving me confidence in its safety and effectiveness.

Overall, this spray is versatile and powerful enough to tackle most pet messes quickly. It’s especially great for those hard-to-clean accidents that seem to set in over time.

Just keep in mind, for very tough or old stains, a little extra elbow grease or reapplication might be necessary.

Good Life Solutions Odor & Stain Remover Spray 16 oz

Good Life Solutions Odor & Stain Remover Spray 16 oz
Pros:
  • Naturally effective on stains
  • Kid and pet safe
  • Eco-friendly and biodegradable
Cons:
  • Less effective on old stains
  • Slightly pricier than chemical options
Specification:
Volume 16 ounces (473 milliliters)
Formulation Type Bio-enzymatic, plant-based, biodegradable
Surface Compatibility Water-safe fabrics and surfaces including mattress, upholstery, carpet, floors, car seats, and cribs
Safety & Certification Kid and pet safe, fragrance-free, made in the USA, cruelty-free
Environmental Impact Biodegradable packaging, fully recyclable container
Application Areas Stains from poo, pee, vomit, blood, wine, and incontinence

Ever had a stubborn stain that just wouldn’t budge, especially on your mattress or furniture? I recently spilled red wine on my sofa after a dinner party, and I was dreading the cleanup.

That’s when I grabbed the Good Life Solutions Odor & Stain Remover Spray.

This spray is surprisingly compact, fitting easily in your hand with a spray nozzle that delivers a fine mist. It felt lightweight but sturdy, and I appreciated that it’s completely fragrance-free—no harsh chemical smell lingering after use.

What really caught my attention is how easy it was to target the stain. I sprayed it directly onto the wine spill, and the bio-enzymatic formula started working immediately.

You don’t need to scrub hard; it just seeps in and breaks down the stain naturally.

Within minutes, I noticed the wine stain visibly fading. It’s safe to use on all water-safe fabrics, so I also tried it on my mattress and dog’s bed.

No residual odor or sticky residue—just a clean, fresh spot that looked like new.

I love that it’s all natural and eco-friendly. The fact that it’s biodegradable and made in the USA gave me peace of mind.

Plus, knowing it’s safe for kids and pets makes it a no-brainer for everyday messes.

On the downside, it’s not a miracle worker for really old or set-in stains. Sometimes, a second application was needed.

Still, for routine messes, it’s a versatile and eco-conscious choice.

Yonynn Mattress & Upholstery Stain Remover Spray

Yonynn Mattress & Upholstery Stain Remover Spray
Pros:
  • Gentle yet powerful cleaning
  • Quick-drying, no residue
  • Multi-purpose use
Cons:
  • Might need multiple applications
  • Slightly pricey for frequent use
Specification:
Active Ingredients Plant-based, non-toxic, eco-friendly formulation
Application Method Spray directly onto stained area, blot gently
Coverage Area Suitable for mattresses, upholstery, carpets, and rugs
Drying Time Quick-drying, typically within minutes
Residue Leaves no sticky residue or overpowering odor
pH Level Likely neutral or mildly acidic/alkaline to ensure fabric safety

When I first sprayed this Yonynn Mattress & Upholstery Stain Remover, I was immediately struck by how light and refreshing the scent was—nothing overpowering, just a clean herbal aroma. The spray bottle feels sturdy in hand, with a fine mist that covers a good area without drenching the fabric.

As I targeted a particularly stubborn urine stain on my mattress, I appreciated how evenly the spray dispersed. It’s easy to control, and the fine mist didn’t soak the fabric, which made blotting simpler and less messy.

The formula’s deep-penetrating action started working right away, breaking down the stain without any harsh chemical smell.

What I really liked is how quickly it dried—no sticky residue or lingering odor. I tried it on my couch and even on some rugs, and it handled everything with ease.

Plus, it’s safe for kids and pets, so I feel comfortable using it around the house without worrying about toxins.

Applying it is straightforward—just spray, wait a few moments, then gently blot. No fancy equipment or complicated steps needed.

It also freshens fabrics by tackling odors at the source, which is a huge plus for my home’s overall scent. Overall, it’s a versatile, effective cleaner that lives up to its promise.

CloroxPro Urine Stain & Odor Remover Spray 32oz

CloroxPro Urine Stain & Odor Remover Spray 32oz
Pros:
  • Fast-acting stain removal
  • Pleasant, fresh scent
  • Versatile for multiple surfaces
Cons:
  • Smaller bottle size
  • Not for extremely old stains
Specification:
Active Ingredient Hydrogen peroxide (powerful stain and odor remover)
Container Size 32 ounces (946 mL)
Suitable Surfaces Carpets, upholstery, mattresses, bed linens, grout, hard non-porous surfaces
Application Environment Indoor and outdoor use, including commercial settings like schools, restaurants, hotels, stadiums
Use Cases Urine stain and odor removal, general stain removal, outdoor stain cleaning
pH Level Likely neutral to slightly alkaline (common for hydrogen peroxide-based cleaners)

Honestly, I didn’t expect this spray to smell so fresh after tackling a stubborn pet urine stain on my mattress. I was bracing for that typical chemical smell, but instead, it left a clean, almost citrusy scent behind.

It’s surprisingly pleasant—like stepping into a freshly cleaned room, not a cleaning aisle.

The spray’s spray nozzle delivers a fine mist that covers large areas quickly, which makes treating mattress stains effortless. When I sprayed it on, I appreciated how quickly it started working—foam and bubbles forming as it broke down the urine crystals.

It really works its magic on the first try, making me confident that I’m not just masking odors.

What really stood out is how versatile this product is. I used it on my mattress, of course, but also on my carpet and even outdoor concrete spots.

The hydrogen peroxide formula seems powerful yet gentle enough to use on soft fabrics without worry. Plus, it’s safe for various surfaces, which is a big plus if you’re tired of juggling multiple cleaners.

It’s a no-brainer for anyone dealing with pet accidents or just needing a reliable stain and odor remover. The fact that it’s designed for commercial use means it’s tough on stains but still safe for home use.

I’d say it’s a solid addition to your cleaning arsenal, especially if you’re tired of lingering smells or stubborn stains.

Of course, it’s not a magic potion—deep-set stains might need more than one application. And at 32oz, it’s not the biggest bottle out there, so you might run out faster if you’re cleaning a lot.

What Is a Mattress Cleaner Spray and How Does It Work?

Best practices for using mattress cleaner sprays include testing the product on a small, inconspicuous area of the mattress first to ensure compatibility, following the manufacturer’s instructions for application, and allowing adequate drying time before putting sheets back on the bed. Regular cleaning, ideally every few months, is recommended to maintain a fresh and healthy sleep environment.

What Ingredients Should You Look for in a Mattress Cleaner Spray?

When searching for the best mattress cleaner spray, consider the following essential ingredients:

  • Enzymatic Cleaners: These are special compounds that break down proteins, fats, and carbohydrates in stains and odors, making them highly effective for organic messes like sweat, urine, or food spills.
  • Baking Soda: Known for its natural deodorizing properties, baking soda helps to neutralize odors in the mattress while also providing gentle abrasive action to lift dirt and grime.
  • Essential Oils: Many mattress cleaners incorporate essential oils such as lavender or tea tree oil, which not only add a pleasant scent but also offer antimicrobial properties to help reduce bacteria and allergens.
  • Non-Toxic Surfactants: These ingredients help to lift dirt and stains from the fabric without leaving harmful residues, ensuring that the mattress remains safe for all users, including children and pets.
  • Vinegar: Often included for its natural cleaning properties, vinegar can help to kill odors and bacteria, making it a useful ingredient in mattress cleaners aimed at sanitizing and refreshing the surface.
  • Hydrogen Peroxide: This ingredient is effective for its antifungal and antibacterial properties, helping to sanitize the mattress while also removing tough stains, making it a popular choice in many cleaning sprays.

What Are the Benefits of Regularly Cleaning Your Mattress?

The benefits of regularly cleaning your mattress are numerous and can significantly enhance your sleeping environment.

  • Improved Sleep Quality: Regular cleaning removes dust mites, allergens, and bacteria that can disrupt sleep. A clean mattress promotes a healthier sleeping environment, leading to better rest and overall well-being.
  • Extended Mattress Lifespan: Keeping your mattress clean helps prevent wear and tear caused by dirt, moisture, and odors. Proper maintenance can extend the life of your mattress, delaying the need for a costly replacement.
  • Better Hygiene: A clean mattress reduces the risk of skin irritations and respiratory issues caused by allergens and germs. Regular cleaning ensures a more hygienic sleeping surface, contributing to better health.
  • Reduction of Odors: Over time, mattresses can absorb odors from sweat, pets, and spills. Cleaning your mattress regularly with a suitable cleaner can eliminate these smells and keep your sleeping space fresh.
  • Enhanced Comfort: A clean mattress can feel more comfortable and inviting, as dirt and debris can create an uneven sleeping surface. Regular maintenance enhances the overall comfort of your bed, making it more enjoyable to sleep on.
  • Prevention of Bed Bugs: Regular cleaning can help detect and prevent bed bug infestations before they become a significant problem. A thorough cleaning routine, including vacuuming and using mattress cleaner spray, can safeguard against these pests.

How Do You Effectively Use a Mattress Cleaner Spray?

To effectively use a mattress cleaner spray, follow these steps:

  • Choose the Right Spray: Selecting the best mattress cleaner spray is crucial for effective cleaning. Look for a product that is specifically formulated for mattresses, as it will tackle stains and odors without damaging the fabric.
  • Vacuum the Mattress: Before applying any cleaner, thoroughly vacuum your mattress to remove dust, dirt, and debris. This step ensures that the cleaner can penetrate deeper into the fabric and perform optimally.
  • Spot Test: Always perform a spot test in an inconspicuous area of the mattress before full application. This precaution helps to check for any adverse reactions or discoloration that could occur with the cleaner.
  • Apply the Cleaner Evenly: Spray the cleaner evenly across the surface of the mattress, keeping the nozzle at a distance recommended by the manufacturer. This method helps to prevent oversaturation and allows for uniform coverage.
  • Let It Sit: Allow the cleaner to sit for the time specified on the product label, usually around 10-15 minutes. This waiting period enables the cleaner to break down stains and neutralize odors effectively.
  • Wipe or Blot: After the recommended time, use a clean cloth to wipe or blot the area. This action helps to lift away any residue, dirt, or remaining stains, providing a cleaner surface.
  • Air Dry the Mattress: Ensure that the mattress is completely dry before putting bedding back on. Proper air drying helps prevent mold and mildew from developing in any damp areas.
  • Regular Maintenance: Incorporate the use of mattress cleaner spray into your regular cleaning routine to maintain freshness and extend the lifespan of your mattress. Frequent cleaning helps to manage allergens and keep your sleeping environment healthy.

What Are the Top Recommended Brands for Mattress Cleaner Spray?

The top recommended brands for mattress cleaner spray are:

  • Zyona: Zyona’s mattress cleaner spray is known for its powerful formula that effectively removes stains and odors while being safe for various fabrics. It contains natural enzymes that break down organic matter, making it an excellent choice for tackling tough stains such as sweat or pet accidents.
  • Carpet and Upholstery Cleaner by Rocco & Roxie: This cleaner is particularly praised for its enzyme-based formula that not only cleans but also deodorizes mattresses. It works well on a variety of surfaces and is safe for humans and pets alike, making it a versatile choice for households.
  • Nature’s Miracle: Nature’s Miracle mattress cleaner is specifically designed to eliminate stains and odors caused by pets. Its bio-enzymatic formula breaks down organic stains effectively, and it is particularly popular among pet owners due to its efficiency and safety.
  • Simple Green: Simple Green offers a mattress cleaner that is environmentally friendly and non-toxic. This cleaner is effective for general cleaning and stain removal, and it can also be used on other surfaces around the home, making it a practical choice for those looking to maintain a clean environment.
  • Biokleen: Biokleen’s mattress cleaner is known for its plant-based ingredients that provide a deep clean without harsh chemicals. This makes it a great option for individuals with allergies or sensitivities, as it effectively removes odors and stains while being gentle on the skin and the environment.

How Can You Remove Stains from Your Mattress?

To effectively remove stains from your mattress, specific cleaning techniques and products can make a significant difference. Follow these steps for tackling various stains:

  1. Identify the Stain Type: Different stains require different treatments. Common types include:
    Blood: Use cold water and a mild detergent.
    Urine: Blot the area with vinegar or a specialized enzyme cleaner.
    Food and Drinks: A mixture of dish soap and warm water typically works well.

  2. Prepare the Area: Strip the bed of all linens and protect the surrounding area with towels to avoid further mess.

  3. Spot Cleaning:
    Use a Mattress Cleaner Spray: A quality mattress cleaner spray can eliminate tough stains and disinfect the surface. Spray a small amount directly on the stain and let it sit as per product instructions.
    Blot, Don’t Rub: Gently blot the stain with a clean cloth or sponge to absorb the liquid. Avoid rubbing, as this can spread the stain.

  4. Rinse and Dry: After treatment, use a damp cloth to wipe away any residue and then allow the mattress to air dry thoroughly before placing linens back on.

By promptly addressing stains and using appropriate cleaning products, you can maintain a fresh and hygienic mattress.

What Common Mistakes Should You Avoid When Cleaning Your Mattress?

When cleaning your mattress, avoiding certain common mistakes can ensure better hygiene and longevity of the mattress.

  • Using Excessive Water: Over-saturating your mattress with water can lead to mold and mildew growth, which can create a health hazard. Instead, use a damp cloth or a spray cleaner with minimal moisture to effectively clean the surface.
  • Neglecting to Vacuum First: Failing to vacuum your mattress before applying any cleaning solution can trap dust mites and allergens in the fabric. Vacuuming removes these particles, making the subsequent cleaning process more effective and ensuring a deeper clean.
  • Skipping Stain Treatment: Ignoring stains can lead to permanent discoloration and unpleasant odors. It’s essential to treat stains with an appropriate cleaner or solution immediately to prevent them from setting in.
  • Using Harsh Chemicals: Many commercial cleaners contain harsh chemicals that can damage the mattress materials and potentially harm your health. Opt for natural or specially formulated mattress cleaner sprays that are safe for use on your specific mattress type.
  • Not Allowing Proper Drying Time: Failing to allow your mattress to dry properly after cleaning can lead to moisture retention and unpleasant odors. Always ensure that your mattress is completely dry before putting on sheets or using it again.
  • Ignoring Manufacturer Instructions: Not following the manufacturer’s care instructions can void your warranty or damage the mattress. Always check for specific cleaning guidelines provided by the manufacturer to avoid any mishaps.
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